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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564266Generated: October 30, 2026

3-Phenylbenzene-1-sulfonyl chloride → (E)-3-[1-(Biphenyl-3-sulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl ester

https://huagongshe.com/reaction/564266

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Phenylbenzene-1-sulfonyl chlorideHCID 3802752—
Reactanttert-butyl (2E)-3-(1H-pyrrol-3-yl)prop-2-enoateHCID 66646340—
Product(E)-3-[1-(Biphenyl-3-sulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl esterHCID 66646405—

Reaction Steps

Starting from (E)-3-(1H-pyrrol-3-yl)-acrylic acid tert-butyl ester (compound D1) and art-known 3-biphenylsulphonylchloride the title compound can be obtained analogously or similarly as described for compound C1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067615B2
Source datasetuspto-grants-2011_11
ORD IDord-ea155079f08d4c1089729074d1bdf4eb
Source noteuspto-grants-2011_11