Benzoyl chloride → HCID 86761444, compound

HRID 564292Notes

Reaction equation

HRID 564292 reaction equation
[Br:1][C:2]1[C:7]([NH:8][C:9](=[O:17])[C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([NH2:16])[CH:11]=2)=[CH:6][CH:5]=[C:4]([O:18][CH:19]([C:24]([F:27])([F:26])[F:25])[C:20]([F:23])([F:22])[F:21])[N:3]=1.[C:28](Cl)(=[O:35])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[Br:1][C:2]1[C:7]([NH:8][C:9](=[O:17])[C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([NH:16][C:28](=[O:35])[C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH:11]=2)=[CH:6][CH:5]=[C:4]([O:18][CH:19]([C:20]([F:21])([F:22])[F:23])[C:24]([F:25])([F:26])[F:27])[N:3]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 86761445HCID 86761445, compound

Product 1

HCID 86761444HCID 86761444, compound

Procedure

Using N-[2 bromo-6-(2,2,2-trifluoro-1-trifluoromethylethoxy)-pyridin-3-yl]3-aminobenzamide and benzoyl chloride, the desired title product was prepared according to the conditions as described in Example 1-4 (Yield: 76%).

Sources & evidence

ORD record
ord-3ec79a9cd0e546c4a066241c4c2c0696
Source dataset
uspto-grants-2011_11
Patent number
US08067638B2

Reaction notes

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