Benzamide → HCID 57814036, compound

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Reaction Steps

The title compound was synthesized in a similar fashion to N-{2-[((3R)-1-{1-[4-(morpholin-4-ylcarbonyl)phenyl]piperidin-4-yl}pyrrolidin-3-yl)amino]-2-oxoethyl}-3-(trifluoromethyl)benzamide, substituting (S)—N-(2-oxo-2-(pyrrolidin-3-ylamino)ethyl)-3-(trifluoromethyl)benzamide for (R)—N-(2-oxo-2-(pyrrolidin-3-ylamino)ethyl)-3-trifluoromethyl)benzamide. 1H-NMR (CD3OD) δ: 1.43-1.68 (m, 2H), 1.62-1.79 (m, 1H), 1.94-2.00 (m, 2H), 2.20-2.38 (m, 2H), 2.55-2.68 (m, 2H), 2.75-2.98 (m, 4H), 3.35-3.40 (m, 2H), 3.60-3.75 (m, 8H), 3.80-3.90 (m, 2H), 4.02 (s, 2H), 4.36-4.46 (m, 1H), 6.99 (d, J=8.4 Hz, 2H), 7.34 (d, J=8.4 Hz, 2H), 7.69 (t, J=7.8 Hz, 1H), 7.87 (t, J=7.5 Hz, 1H), 8.14 (d, J=7.8 Hz, 1H), 8.22 (s, 1H). MS m/z: 588 (M+1).

Provenance & Evidence