Benzamide → N-(2-oxo-2-{[(3S)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl]amino}ethyl)-3-(trifluoromethyl)benzamide

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The title compound was synthesized in a similar fashion to N-(2-oxo-2-{[(3R)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl]amino}ethyl)-3-(trifluoromethyl)benzamide, substituting (S)—N-(2-oxo-2-(pyrrolidin-3-ylamino)ethyl)-3-trifluoromethyl)benzamide for (R)—N-(2-oxo-2-(pyrrolidin-3-ylamino)ethyl)-3-(trifluoromethyl)benzamide 1H-NMR (CD3OD) δ: 1.69-1.77 (m, 2H), 2.01-2.09 (m, 3H), 2.39-2.46 (m, 1H), 3.24-3.44 (in 5H), 3.51-3.59 (m, 2H), 3.96-4.09 (m, 4H), 4.50-4.53 (m, 1H), 7.70 (t, J=7.9 Hz, 1H), 7.87 (d, J=7.5 Hz, 1H), 8.15 (d, J=8.4 Hz, 1H), 8.21 (s, 1H), 8.34 (s, 1H). MS m/z: 400 (M+1).

Provenance & Evidence