Benzoyl chloride, 3,4-dichloro- → HCID 57813990, compound

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Reaction Steps

The title compound was synthesized in similar fashion to 3,4-Dichloro-N-[2-({(3R)-1-[1-(4-methoxyphenyl)piperidin-4-yl]pyrrolidin-3-yl}amino)-2-oxoethyl]benzamide, substituting 3-chlorobenzoylchloride for 3,4-dichlorobenzoylchloride, and was isolated as a white solid. 1H-NMR (CDCl3) δ: 1.63-1.64 (m, 3H), 1.86-1.90 (m, 2H), 2.01-2.44 (m, 3H), 2.56-2.74 (m, 4H), 2.92-3.00 (m, 1H), 3.43 (d, J=11.1 Hz, 2H), 3.70 (s, 3H), 4.04 (d, J=4.2 Hz, 2H), 4.43 (b, 1H), 6.55 (d, J=6.0 Hz, 1H), 6.74-6.85 (m, 4H), 7.06 (b, 1H), 7.30 (t, J=8.5 Hz, 1H), 7.42 (d, J=7.5 Hz, 2H), 7.63 (d, J=8.1 Hz, 1H), 7.27 (s, 1H). MS m/z: 471 (M+1).

Provenance & Evidence