反应详情

To 3-[(methyloxy)carbonyl]benzoic acid (0.18 g, 1.0 mmol) was added lithium triethyl borohydride (3.0 mL, 1.0 M in THF, 3.0 mmol) while stirring. The mixture was stirred for 3 h and then quenched with NH4Cl (sat.) and acidified with HCl (aq.). This solution was extracted with EtOAc, and the extract was dried over Na2SO4, filtered and concentrated to afford the title compound 0.136 g (89%). LC-MS m/z 153 (M+H)+.

1. stirringThe mixture was stirred for 3 h
2. customquenched with NH4Cl (sat.)
3. extractionThis solution was extracted with EtOAc
4. dry with materialthe extract was dried over Na2SO4
5. filtrationfiltered
6. concentrationconcentrated