HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3,5-dichloropyridine → 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3,5-dichloropyridin-4-yl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3,5-dichloropyridine | HCID 89888 | — |
| Reactant | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester | HCID 54119345 | — |
| Product | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3,5-dichloropyridin-4-yl)amide | HCID 86756186 | 74.8% |
Reaction Steps
Starting from 2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester (0.20 g) and 4-amino-3,5-dichloropyridine (0.11 g). Purification by trituration with ether gave the title compound (0.16 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169090A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-3a2b10331b704efe96754c1f25328f11 |
| Source note | uspto-grants-2001_01 |