HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-4-aminopyridine → 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3-methoxypyridin-4-yl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-4-aminopyridine | HCID 3016738 | — |
| Reactant | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester | HCID 54119345 | — |
| Product | 2-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid (3-methoxypyridin-4-yl)amide | HCID 54172037 | 86.1% |
Reaction Steps
Starting from 2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester (170 mg) and 4-amino-3-methoxypyridine (120 mg). Purification by column chromatography on silica eluting with ethyl acetate gave the title compound (0.14 g) as an off white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169090A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-dec932833ab24c1abd7ea02adfcc858b |
| Source note | uspto-grants-2001_01 |