1-Methyl-5-(tri-n-butylstannyl)imidazole → 4-(4-Benzyloxyanilino)-6-(N-methylimidazol-5-yl)pyrido[3,4-d]pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-5-(tri-n-butylstannyl)imidazole	HCID 10915651	—
Reactant	4-(4-Benzyloxyanilino)6-chloropyrido[3,4-d]pyrimidine	HCID 21952168	—
Product	4-(4-Benzyloxyanilino)-6-(N-methylimidazol-5-yl)pyrido[3,4-d]pyrimidine	HCID 22112846	—

Reaction Steps

Prepared according to Procedure B from 4-(4-benzyloxyanilino)-6-chloropyrido[3,4-d]pyrimidine and 5-(tri-n-butylstannyl)-N-methylimidazole (prepared according to the published method: Acta Chem. Scand., (1993), 47(1), 57); δH [2H6]-DMSO 10.00 (1H,s), 9.15 (1H,s), 8.65 (1H,s), 8.60 (1H, s), 7.80 (1H,s), 7.61(2H,d), 7.50 (1H,s), 7.25-7.49 (5H,m), 7.10 (2H,d), 5.13 (2H,s), 3.98 (3H,s); m/z (M+1)+409.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06169091A
Source dataset	uspto-grants-2001_01
ORD ID	ord-6d2749bea28240bdb665dc105264c931
Source note	uspto-grants-2001_01