HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 4-(4-Benzyloxyanilino)-6-(1-methylpiperazin-4-yl)-pyrido[3,4-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4-(4-Benzyloxyanilino)6-chloropyrido[3,4-d]pyrimidine | HCID 21952168 | — |
| Product | 4-(4-Benzyloxyanilino)-6-(1-methylpiperazin-4-yl)-pyrido[3,4-d]pyrimidine | HCID 22112891 | — |
Reaction Steps
Prepared according to Procedure C from 4-(4-benzyloxyanilino)-6-chloropyrido[3,4-d]pyrimidine and 1-methylpiperazine; δH (CDCl3) 9.00 (1H,s), 8.58 (1H,s), 7.59 (2H, d), 7.28-7.40 (5H,m), 7.02 (2H,d), 6.59 (1H,s), 5.08 (2H,s), 3.60-3.74 (4H,m), 2.52-2.64 (4H,m), 2.40 (3H,s); m/z (M+1)+427.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169091A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-3b712a5112c14c91b350100923dc8022 |
| Source note | uspto-grants-2001_01 |