2-(Methylamino)ethanol → 6-[N-Methyl-N-(2-hydroxyethyl)amino]-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	2-(Methylamino)ethanol	HCID 8016	—
Reactant	6-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine	HCID 21952165	—
Product	6-[N-Methyl-N-(2-hydroxyethyl)amino]-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine	HCID 22112892	—

Reaction Steps

Prepared according to Procedure C from 6-chloro4-(4-phenylsulphonylanilino)-pyrido[3,4-d]pyrimidine and 2-(methylamino)ethanol; δH [2H6]-DMSO 9.99 (1H,s), 8.89 (1H,s), 8.48 (1H,s), 8.20 (2H,d), 7.97-8.09 (4H,m), 7.60-7.78 (3H,m), 7.27 (1H,s), 4.27 (1H,t), 3.75-3.85 (2H,m), 3.60-3.71 (2H,m), 3.21 (3H,s); m/z (M+1)+436.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06169091A
Source dataset	uspto-grants-2001_01
ORD ID	ord-900db69fd02f4b23a9ed6161938dbf10
Source note	uspto-grants-2001_01