HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Sulfate → 2-Amino-5-bromo-4-methoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Sulfate | HCID 24436 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Amino-4-methoxybenzaldehyde | HCID 323503 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Amino-5-bromo-4-methoxybenzaldehyde | HCID 59325258 | 56% |
Reaction Steps
To a stirred solution of 2-amino-4-methoxybenzaldehyde (6 g, 39.7 mmol) in dichloromethane (100 mL) was added N-bromosuccinimide (7 g, 39.7 mmol). The reaction mixture was diluted with dichloromethane and water. The separated organic layer was dried sodium sulfate, filtered and concentrated to give the title compound (5 g, 56%) as a yellow solid. MS (ES+) C8H8BrNO2 requires: 229, 231, found: 230, 232 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434700B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-1203a7025ae741efb01dce4fb28ead02 |
| Source note | uspto-grants-2016_09 |