HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 22112999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 22113061 | HCID 22113061 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 22112999 | HCID 22112999 | 83.5% |
Reaction Steps
A solution of 4-chloro-2-ethyl-8-methoxyquinoline (4.0 g) in 48% hydrobromic acid (80 ml) was refluxed for 2 days. The mixture was adjusted to pH 12 with 28% ammonia solution. The precipitate was collected by vacuum filtration, and was washed with water and hexane to give 4-chloro-2-ethyl-8-hydroxyquinoline (3.13 g) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169095A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-453678c0a1ab4d67abc3310f1164200e |
| Source note | uspto-grants-2001_01 |