HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1H-indole-2-carboxylate → Methyl N-methylindole-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1H-indole-2-carboxylate | HCID 70992 | — |
| Reactant | Ethyl 4-chloro-1H-indole-2-carboxylate | HCID 11075028 | — |
| Reactant | 2-(4-iodobutoxy)tetrahydropyran | HCID 11108838 | — |
| Product | Methyl N-methylindole-6-carboxylate | HCID 639843 | — |
Reaction Steps
The title compound was prepared in a manner similar to Reference Example 5 (23) except that 2-(4-iodobutoxy)tetrahydropyran and ethyl 4-chloro-2-indolecarboxylate was used in place of 2-(2-iodoethoxy)tetrahydropyran and methyl 2-indolecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06169107A |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-96386448747c402bb752190704f3eb39 |
| Source note | uspto-grants-2001_01 |