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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 564991Generated: October 31, 2026

Methyl 4-(benzyloxy)-2-methylbenzoate → (4-(Benzyloxy)-2-methylphenyl)methanol

https://huagongshe.com/reaction/564991

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(benzyloxy)-2-methylbenzoateHCID 21194710—
ReactantAluminium lithium hydrideHCID 21226445—
SolventTetrahydrofuranHCID 8028—
Product(4-(Benzyloxy)-2-methylphenyl)methanolHCID 230778480.1%

Reaction Conditions

Temperature0 °C

Reaction Steps

A suspension of 0.11 g (2.93 mmol) of lithium aluminum hydride in 20 ml of tetrahydrofuran was cooled to 0° C. A solution of 0.75 g (2.93 mol) of methyl 4-benzyloxy-2-methylbenzoate in 20 ml of tetrahydrofuran was added dropwise to the suspension at DOC. After stirring at 0° C. for 2 hours, the reaction mixture was treated in a conventional manner to give 0.66 g of 4-benzyloxy-2-methylbenzyl alcohol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06169107A
Source datasetuspto-grants-2001_01
ORD IDord-5c5ee67429b34a8ab831d3b07564fe0c
Source noteuspto-grants-2001_01