Ethyl 6-benzyloxy-1-methyl-4-trifluoromethyl-2-indolecarboxylate → Ethyl 6-hydroxy-1-methyl-4-trifluoromethyl-2-indolecarboxylate

Participants

Reaction Steps

The reaction was carried out in a manner similar to Reference Example 15 a) except for using 2.23 g (5.91 mmol) of ethyl 6-benzyloxy-1-methyl-4-trifluoromethyl-2-indolecarboxylate, 0.3 g of 10% palladium/carbon and 50 ml of tetrahydrofuran. Ethyl 6-hydroxy-1-methyl-4-trifluoromethyl-2-indolecarboxylate was thus obtained in an amount of 1.70 g.

Provenance & Evidence