Guanidine Hydrochloride → HCID 178485145, compound

Participants

Reaction Steps

The reaction was carried out in a manner similar to Example 186 b) except for using 0.28 g (0.70 mmol) of ethyl 4-chloro-7-[4-(dimethylaminomethyl)benzyloxy]-1-methyl-2-indolecarboxylate, 1.52 g (16.0 mmol) of guanidine hydrochloride, 0.86 g (16.0 mmol) of sodium methoxide and 40 ml of methanol. Thus, 0.10 g (29.3%) of 4-chloro-7-[4-(dimethylaminomethyl)benzyloxy]-1-methyl-2-indoloylguanidine dihydrochloride was obtained.

Provenance & Evidence