Urea → 4-p-Tolylethynylphenyl 4-vinylcyclohexanecarboxylate

Participants

Reaction Steps

5.0 g of 4-vinylcyclohexanecarboxylic acid, 6.7 g of 4-p-tolylethynylphenol, 4.0 g of 4-(dimethylamino)pyridine and 250 ml of toluene were mixed at RT, 7.3 g of DCC in 50 ml of toluene were added, and the mixture was stirred vigorously overnight at RT, during which the urea formed precipitated. 1 g of oxalic acid was then added, and the mixture was stirred at RT for a further hour in order to destroy the excess DCC. The conventional work-up gave 4-p-tolylethynylphenyl 4-vinylcyclohexanecarboxylate in the form of colorless crystals.

Provenance & Evidence