Dichloromethane → HCID 86756213, compound

Participants

Reaction Steps

36.6 g of [4-(4-p-tolylethynylphenyl)cyclohexyl]methanol were mixed with 300 ml of dichloromethane, and a mixture of 21 g of Celite and 28.5 g of pyridinium chlorochromate (PCC) were added under a nitrogen atmosphere. The reaction mixture was stirred overnight at RT. 100 ml of isopropanol were then added to the black suspension, and the mixture was stirred at RT for 1½ hours in order to destroy the excess PCC. This suspension was then filtered, and the filtrate was subjected to conventional work-up, giving 4-(4-p-tolylethynylphenyl)cyclohexanecarbaldehyde in the form of a colorless solid.

Provenance & Evidence