HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 73689151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 86756213 | HCID 86756213 | — |
| Catalyst | Phosphonium, ethyltriphenyl-, bromide (1:1) | HCID 73727 | — |
| Product | HCID 73689151 | HCID 73689151 | — |
Reaction Steps
14.03 g of 4-(4-p-tolylethynylphenyl)cyclohexanecarbaldehyde were dissolved in 100 ml of THF, and 15.22 g of ethyltriphenylphosphonium bromide were added quickly under a nitrogen atmosphere. 4.6 g of potassium tert-butoxide were then added in portions. The suspension was stirred overnight at RT, then poured into water and neutralized using 2 N hydrochloric acid solution. Conventional work-up gave 1-propenyl-4-(4-p-tolylethynylphenyl)cyclohexane as an E/Z isomer mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06171664B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-2717ecce04344f8e8bbe43e1cba24dc5 |
| Source note | uspto-grants-2001_01 |