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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565194Generated: October 29, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/565194

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride 11 is amidated with morpholine 12 by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172044B2
Source datasetuspto-grants-2001_01
ORD IDord-87d57140c0e74f01ac3419cf49b777e3
Source noteuspto-grants-2001_01