Potassium Nitrate → 2H-3,1-Benzoxazin-2-one, 6-bromo-1,4-dihydro-5-methyl-8-nitro-

HRID 565203Notes

Reaction equation

HRID 565203 reaction equation
[Br:1][C:2]1[CH:12]=[CH:11][C:5]2[NH:6][C:7](=[O:10])[O:8][CH2:9][C:4]=2[C:3]=1[CH3:13].[N+:14]([O-])([O-:16])=[O:15].[K+]>OS(O)(=O)=O>[Br:1][C:2]1[CH:12]=[C:11]([N+:14]([O-:16])=[O:15])[C:5]2[NH:6][C:7](=[O:10])[O:8][CH2:9][C:4]=2[C:3]=1[CH3:13]

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 107765166-Bromo-5-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one

Product 1

HCID 107556822H-3,1-Benzoxazin-2-one, 6-bromo-1,4-dihydro-5-methyl-8-nitro-

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To a solution of 6-bromo-5-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one (0.726 g, 3 mmol) in concentrate H2SO4 (4 mL), KNO3 (0.303 g, 3 mmol) was added at 0° C. Reaction mixture stirred 14 hours and poured over crushed ice. Yellow precipitate was obtained, which was filtered and dried. (Yield: 0.782=91%);

Workup

  1. customReaction mixture
  2. additionpoured
  3. customover crushed ice
  4. customYellow precipitate was obtained
  5. filtrationwhich was filtered
  6. customdried

Sources & evidence

ORD record
ord-bcc2be02e0134a17bc6a7d4e0d4af84b
Source dataset
uspto-grants-2001_01
Patent number
US06172065B2

Reaction notes

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