Potassium Nitrate → 5,6-Dimethyl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione

HRID 565209Notes

Reaction equation

HRID 565209 reaction equation
[CH3:1][C:2]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[NH:4][C:5](=[O:14])[C:6](=[O:13])[NH:7]2.[N+:15]([O-])([O-:17])=[O:16].[K+]>OS(O)(=O)=O>[CH3:1][C:2]1[C:11]([CH3:12])=[C:10]([N+:15]([O-:17])=[O:16])[CH:9]=[C:8]2[C:3]=1[NH:4][C:5](=[O:14])[C:6](=[O:13])[NH:7]2

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 6855815,6-Dimethylquinoxaline-2,3-diol

Product 1

HCID 212680925,6-Dimethyl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

To a solution of 5,6-dimethyl-1,4dihydro-quinoxaline-2,3-dione (28.5 g, 150 mmol) in concentrated H2SO4 (50 mL) was added KNO3 (15.15 g, 150 mmol) portionwise keeping temperature below 5° C. Reaction mixture was stirred for 2 hours and poured over ice. Yellow precipitate was filtered, washed, and air dried.

Workup

  1. customtemperature below 5° C
  2. customReaction mixture
  3. additionpoured over ice
  4. filtrationYellow precipitate was filtered
  5. washwashed
  6. customair dried

Sources & evidence

ORD record
ord-23d5b5c36be74c2c9d69697e6bb1e80a
Source dataset
uspto-grants-2001_01
Patent number
US06172065B2

Reaction notes

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