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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565312Generated: October 29, 2026

HCID 54465219, compound → 1-[(4-Methoxyphenyl)sulfonyl]cyclopentanecarboxylic acid

https://huagongshe.com/reaction/565312

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54465219HCID 54465219—
SolventMethanolHCID 887—
SolventSodium HydroxideHCID 14798—
Product1-[(4-Methoxyphenyl)sulfonyl]cyclopentanecarboxylic acidHCID 15130519—

Reaction Steps

1-(4-Methoxy-benzenesulfonyl)-cyclopentanecarboxylic acid was prepared starting from 1-(4-methoxy-benzenesulfonyl)-cyclopentanecarboxylic acid ethyl ester (2.2 g, 7.0 mmol) dissolved in methanol (50 ml) and 10 N NaOH (30 ml). The resulting reaction mixture was worked up as outlined in Example 9. Yield 1.66 g, 83%. Colorless solid; mp 112-115° C.; MS: 285 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172057B2
Source datasetuspto-grants-2001_01
ORD IDord-089cdd4f58814b408daffb5738475f67
Source noteuspto-grants-2001_01