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HRID56534

反应详情

EQUATION

反应方程式

HRID 56534 的结构方程式

REACTANTS

反应物

2
结构：COc1cc(-c2ccco2)cc(OC)c1C
HCID58432024

未命名化合物

结构：COC(C(=O)N(C)OC)c1ccc(-c2nnc(C)o2)cc1
HCID58432086

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2ccc(C(=O)C(OC)c3ccc(-c4nnc(C)o4)cc3)o2)cc(OC)c1C
HCID58432011

未命名化合物

收率 29%

PROCEDURE

实验过程

N,2-Dimethoxy-N-methyl-2-(4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl)acetamide was reacted with 2-(3,5-dimethoxy-4-methylphenyl)furan according to the procedure used for the synthesis of Example 12. Purification by chromatography (EtOAc-hexanes) gave 1-(5-(3,5-dimethoxy-4-methylphenyl)furan-2-yl)-2-methoxy-2-(4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl)ethanone as a yellow foam (0.148 g, 29% yield). MS: m/z 449.2 [M+H]+.

WORKUP

后处理

  1. customused for the synthesis of Example 12
  2. customPurification by chromatography (EtOAc-hexanes)