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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565437Generated: October 31, 2026

Oxalyl chloride → (r)-3-Triisopropylsilyloxybutyryl chloride

https://huagongshe.com/reaction/565437

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxalyl chlorideHCID 65578—
Reactant(r)-3-Triisopropylsilyloxybutyric acidHCID 14084664—
SolventDichloromethaneHCID 6344—
Product(r)-3-Triisopropylsilyloxybutyryl chlorideHCID 14084666—

Reaction Steps

0.0475 mol (12.36 g ) of the product from stage 2 is dissolved in 200 ml of absolute dichloromethane and treated with stirring with 0.0523 mol (6.64 g) of oxalyl chloride. After 5 hours at room temperature, the mixture is concentrated under reduced pressure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172103B2
Source datasetuspto-grants-2001_01
ORD IDord-4e4be5571e5f434a9b027812224dbd29
Source noteuspto-grants-2001_01