Furan-2-boronic acid → 2-(4-(Difluoromethoxy)-3,5-dimethoxyphenyl)furan

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Furan-2-boronic acid	HCID 2734357	—
Edukt	5-Bromo-2-(difluoromethoxy)-1,3-dimethoxybenzene	HCID 58432071	—
Produkt	2-(4-(Difluoromethoxy)-3,5-dimethoxyphenyl)furan	HCID 58432053	—

Reaktionsschritte

5-Bromo-2-(difluoromethoxy)-1,3-dimethoxybenzene was coupled with 2-furylboronic acid following the procedure for the synthesis of Example 21. Purification by chromatography (0-30% EtOAc-hexanes) provided 2-(4-(difluoromethoxy)-3,5-dimethoxyphenyl)furan as a white crystalline material (0.555 g, 67% yield).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09434707B2
Quelldatensatz	uspto-grants-2016_09
ORD ID	ord-658b142ae1714a849ab0f4d9cedf4a35
Quellennotiz	uspto-grants-2016_09