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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565526Generated: October 31, 2026

Ethanol → HCID 57325182, compound

https://huagongshe.com/reaction/565526

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 10420726—
Reactant(2s)-Glycidyl indol-4-yl etherHCID 10943254—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 57325182HCID 57325182—

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.389 g, 2.05 mmol) and 6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.400 g, 1.87 mmol) using ethanol as reaction solvent. Yield 0.260 g (35%) as an orange foam. mp 99-103° C. (dec). FDMS m/e=401 (M+ of free base). α[D]589=+5.1 (c=0.98, dimethylsulfoxide).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172073B2
Source datasetuspto-grants-2001_01
ORD IDord-23b1d37d43ca4c66b34fa53a655feb8d
Source noteuspto-grants-2001_01