HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxyindole → 5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxyindole | HCID 13872 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole | HCID 108029 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Preparation 30 from 5-methoxyindole (5.0 g, 34 mmol) and 4-piperidone hydrochloride hydrate (10.0 g, 65 mmol). The product was isolated as a yellow solid. Yield 6.1 g (79%). mp 191-195° C. FDMS m/e=228 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172073B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-bd1187a3403742a2804eaad327a87abb |
| Source note | uspto-grants-2001_01 |