HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-chloro-1H-indole → 7-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-chloro-1H-indole | HCID 104644 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Product | 7-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 18545849 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Preparation 30 from 7-chloroindole (0.70 g, 4.6 mmol) and 4-piperidone hydrochloride hydrate (1.4 g, 9.2 mmol). The product was isolated as a yellow solid. Yield 0.80 g (75%). mp 205-208° C. FDMS m/e=234 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172073B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-866b6c5dc15d427dbdacd75ee95cda60 |
| Source note | uspto-grants-2001_01 |