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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565554Generated: October 25, 2026

Potassium Carbonate → HCID 21268295, compound

https://huagongshe.com/reaction/565554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant4-(3-chloropropoxy)-1H-indoleHCID 11694169—
Reactant6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 18545981—
ProductHCID 21268295HCID 21268295—

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 192 from 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.70 g, 2.6 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.60 g, 2.9 mmol) and potassium carbonate (0.48 g, 3.5 mmol). The product was isolated as a white granular solid. Yield 220 mg (19%). mp 224-227° C. FDMS m/e=439 (M+ of free base).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172073B2
Source datasetuspto-grants-2001_01
ORD IDord-6751b059e9b14c1791c8f27c52db516b
Source noteuspto-grants-2001_01