HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 21268351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(3-chloropropoxy)-1H-indole | HCID 11694169 | — |
| Reactant | HCID 21268353 | HCID 21268353 | — |
| Product | HCID 21268351 | HCID 21268351 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Example 192 from 6,7-dichloro-3-(piperidin-4-yl)-1H-indole (0.80 g, 3.0 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.64 g, 3.1 mmol) and potassium carbonate (0.83 g, 6.0 mmol). The product was isolated as a tan foam. Yield 278mg, 21%. mp 160-165° C. FDMS m/e=441 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172073B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-c0157ee859dc4b94bc635e55063584d4 |
| Source note | uspto-grants-2001_01 |