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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56556Generated: October 26, 2026

2-(4-Bromo-3,5-dimethoxyphenyl)furan → 1-(5-(4-Bromo-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-(2-methyl-2H-tetrazol-5-yl)phenyl)ethanone

https://huagongshe.com/reaction/56556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromo-3,5-dimethoxyphenyl)furanHCID 58431988—
ReactantN,2-dimethoxy-N-methyl-2-(4-(2-methyl-2H-tetrazol-5-yl)phenyl)acetamideHCID 58432087—
Product1-(5-(4-Bromo-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-(2-methyl-2H-tetrazol-5-yl)phenyl)ethanoneHCID 58432128—

Reaction Steps

1-(5-(4-Bromo-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-(2-methyl-2H-tetrazol-5-yl)phenyl)ethanone was prepared from 2-(4-bromo-3,5-dimethoxyphenyl)furan and N,2-dimethoxy-N-methyl-2-(4-(2-methyl-2H-tetrazol-5-yl)phenyl)acetamide according to the procedure used in Example 30. Purification by chromatography (40% EtOAc/hexanes) gave the product as a pale yellow solid (0.106 g, 29% yield). MS: m/z 513.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434707B2
Source datasetuspto-grants-2016_09
ORD IDord-2356f83da6e045a59f25e343ba28593f
Source noteuspto-grants-2016_09