(2s)-Glycidyl indol-4-yl ether → HCID 57101122, compound

Participants

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 193 from 4-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.50 g, 2.3 mmol) and (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.44 g, 2.3 mmol). The resulting free base was obtained as a yellow foam. Yield 0.14 g (15%). mp 90-95° C. FDMS m/e=405 (M+ of free base).

Provenance & Evidence