HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 70214575, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | (2s)-Glycidyl indol-4-yl ether | HCID 10943254 | — |
| Reactant | 7-Methyl-3-(4-piperidinyl)-1H-indole | HCID 11298855 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 70214575 | HCID 70214575 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.280 g, 1.48 mmol) and 7-methyl-3-(piperidin-4-yl)-1H-indole ( 0.290 g, 1.39 mmol) using ethanol as reaction solvent. Yield 0.320 g (57%) as a tan foam. FDMS m/e=404 (M+ of free base). α[D]589=11.6 (c=0.98, dimethylsulfoxide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172073B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-8b960eaa1d0d43d1863671ae60eb91c7 |
| Source note | uspto-grants-2001_01 |