HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 57285399, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | (2s)-Glycidyl indol-4-yl ether | HCID 10943254 | — |
| Reactant | 6-Methyl-3-(piperidin-4-yl)-1H-indole | HCID 21268318 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 57285399 | HCID 57285399 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.145 g, 0.767 mmol) and 6-methyl-3-(piperidin-4-yl)-1H-indole (0.150 g, 0.697 mmol) using ethanol as reaction solvent. Yield 0.140 g (49%) as a tan foam. FDMS m/e=403 (M+ of free base). α[D]589=+3.8 (c=0.98, dimethylsulfoxide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172073B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-0ee4165f28964f54afd7b089ec5e41b4 |
| Source note | uspto-grants-2001_01 |