HRID565666

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2762420

4-[(Diphenylmethoxy)methyl]piperidine

C19H23NO

结构：Cc1c(C)c2c(c(C)c1NC(=O)OC(C)(C)C)CC(C)(CCBr)O2

HCID54438432

未命名化合物

PRODUCTS

生成物

结构：Cc1c(C)c2c(c(C)c1NC(=O)OC(C)(C)C)CC(C)(CCN1CCC(COC(c3ccccc3)c3ccccc3)CC1)O2

HCID54143297

未命名化合物

收率 82%

PROCEDURE

实验过程

Using tert-butyl [2-(2-bromoethyl)-2,3-dihydro-2,4,6,7-tetramethylbenzofuran-5-yl]carbamate and 4-[(diphenylmethoxy)methyl]piperidine, the procedure of Reference Example 58 was otherwise repeated to provide the title compound. Yield 82%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-12bf5ecd74f94b82bd823b4e88729577
来源数据集: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06172085B2
来源说明: uspto-grants-2001_01

反应 SMILES

Br[CH2:2][CH2:3][C:4]1([CH3:24])[CH2:8][C:7]2[C:9]([CH3:23])=[C:10]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:11]([CH3:14])=[C:12]([CH3:13])[C:6]=2[O:5]1.[C:25]1([CH:31]([C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)[O:32][CH2:33][CH:34]2[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]2)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:25]1([CH:31]([C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)[O:32][CH2:33][CH:34]2[CH2:39][CH2:38][N:37]([CH2:2][CH2:3][C:4]3([CH3:24])[CH2:8][C:7]4[C:9]([CH3:23])=[C:10]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:11]([CH3:14])=[C:12]([CH3:13])[C:6]=4[O:5]3)[CH2:36][CH2:35]2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1