HRID565697

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10999607

5,5-diphenylpentanoic Acid

C17H18O2

结构：Cc1c(C)c2c(c(C)c1N)CC(C)(CN1CCNCC1)O2

HCID21997779

未命名化合物

PRODUCTS

生成物

结构：Cc1c(C)c2c(c(C)c1N)CC(C)(CN1CCN(C(=O)CCCC(c3ccccc3)c3ccccc3)CC1)O2

HCID22110996

未命名化合物

收率 86%

PROCEDURE

实验过程

Using 2,3-dihydro-2,4,6,7-tetramethyl-2-[(1-piperazinyl)methyl]-5-benzofuranamine and 5,5-diphenylvaleric acid, the procedure of Example 10 was otherwise repeated to provide the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9ef50c398596443b9c3c67d3f2978641
来源数据集: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06172085B2
来源说明: uspto-grants-2001_01

反应 SMILES

[CH3:1][C:2]1([CH2:15][N:16]2[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]2)[CH2:6][C:5]2[C:7]([CH3:14])=[C:8]([NH2:13])[C:9]([CH3:12])=[C:10]([CH3:11])[C:4]=2[O:3]1.[C:22]1([CH:28]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH2:29][CH2:30][CH2:31][C:32](O)=[O:33])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:35]1([CH:28]([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:29][CH2:30][CH2:31][C:32]([N:19]2[CH2:20][CH2:21][N:16]([CH2:15][C:2]3([CH3:1])[CH2:6][C:5]4[C:7]([CH3:14])=[C:8]([NH2:13])[C:9]([CH3:12])=[C:10]([CH3:11])[C:4]=4[O:3]3)[CH2:17][CH2:18]2)=[O:33])[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=1