Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | HCID 22468532 | HCID 22468532 | — |
| Reactant | HCID 178507982 | HCID 178507982 | — |
| Product | HCID 22611715 | HCID 22611715 | — |
Reaction Steps
3.5 ml of isonipecotate was added to a solution of 1.0 g of 4N-benzyl-2-chloro-5-nitropyrimidineamine (Reference Example 2) in 35 ml of acetonitrile and the suspension was stirred overnight. 35 ml of ethanol was added to the suspension, cooled to 5° C. and stirred for 1 hour. Filtration afforded 0.91 g of the yellowish title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06172227B2 |
|---|
| Source dataset | uspto-grants-2001_01 |
|---|
| ORD ID | ord-aa00ca60bcd944d89e0e29ea2e116d37 |
|---|
| Source note | uspto-grants-2001_01 |
|---|
