Cyclopropylamine → HCID 22111557, compound

HRID 565743Notes

Reaction equation

HRID 565743 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][S:13](Cl)(=[O:15])=[O:14].[CH:17]1([NH2:20])[CH2:19][CH2:18]1>>[CH:17]1([NH:20][S:13]([CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][Br:1])(=[O:15])=[O:14])[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 22111641HCID 22111641, compound

Product 1

HCID 22111557HCID 22111557, compoundYield 96%

Procedure

The reaction was carried out in the same manner as in Preparation Example 3 except for using 11-bromoundecanesulfonyl chloride (2.29g, 6.85 mmol) in place of 6-bromohexanesulfonyl chloride, and cyclopropylamine (860 mg, 15.1 mmol), to give N-cyclopropyl-11-bromoundecanesulfonamide (2.33 g) as colorless crystals.

Workup

  1. customThe reaction was carried out in the same manner as in Preparation Example 3 except

Sources & evidence

ORD record
ord-55dfa219131f4e7b8999ec399f28b04f
Source dataset
uspto-grants-2001_01
Patent number
US06172228B2

Reaction notes

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