HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide → 1-(5-(4-Chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide | HCID 58431993 | — |
| Reactant | 2-(4-Chloro-3,5-dimethoxyphenyl)furan | HCID 58432088 | — |
| Product | 1-(5-(4-Chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone | HCID 58432104 | — |
Reaction Steps
1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone was prepared from 2-(4-chloro-3,5-dimethoxyphenyl)furan and N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide according to the procedure used in Example 30. Purification by chromatography (70% EtOAc/hexanes) gave the product as a pale yellow solid (0.201 g, 43% yield). MS: m/z 472.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434707B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-b80ffb12e98f41a7995d279ad951fb07 |
| Source note | uspto-grants-2016_09 |