反应详情

In ethanol (100 ml) was dissolved 1-(3-nitrobenzyl)piperidine (32.2 g), and to the mixture was added dried 10% palladium on carbon (1.61 g). Under hydrogen atmosphere, the mixture was stirred at room temperature under atmospheric pressure for 24 hours. The palladium was filtered off, and the filtrate was concentrated. The residue was recrystallized from diisopropylether-hexane to give 1-(3-aminobenzyl)piperidine (15.8 g) as colorless crystals.

1. additionto the mixture was added
2. dry with materialdried 10% palladium on carbon (1.61 g)
3. filtrationThe palladium was filtered off
4. concentrationthe filtrate was concentrated
5. customThe residue was recrystallized from diisopropylether-hexane