HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinemethanol,a-(4-nitrophenyl)- → (4-Aminophenyl) (2-pyridyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinemethanol,a-(4-nitrophenyl)- | HCID 10353788 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Aminophenyl) (2-pyridyl)methanol | HCID 10420323 | 45% |
Reaction Steps
In ethanol (50 ml) was dissolved (4-nitrophenyl)(2-pyridyl)methanol (2.30 g), and to the mixture was added dried 10% palladium on carbon (0.12 g). Under hydrogen atmosphere, the mixture was stirred at room temperature under atmospheric pressure for 19 hours. The palladium was filtered off, and the filtrate was concentrated. The residue was recrystallized from ethyl acetate-hexane to give (4-aminophenyl) (2-pyridyl)methanol (1 .90 g) as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06172061B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-aeabc0c822a54a999a9229d25cba61ee |
| Source note | uspto-grants-2001_01 |