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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565862Generated: October 28, 2026

2-Pyridinemethanol,a-(4-nitrophenyl)- → (4-Aminophenyl) (2-pyridyl)methanol

https://huagongshe.com/reaction/565862

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyridinemethanol,a-(4-nitrophenyl)-HCID 10353788—
SolventEthanolHCID 702—
Product(4-Aminophenyl) (2-pyridyl)methanolHCID 1042032345%

Reaction Steps

In ethanol (50 ml) was dissolved (4-nitrophenyl)(2-pyridyl)methanol (2.30 g), and to the mixture was added dried 10% palladium on carbon (0.12 g). Under hydrogen atmosphere, the mixture was stirred at room temperature under atmospheric pressure for 19 hours. The palladium was filtered off, and the filtrate was concentrated. The residue was recrystallized from ethyl acetate-hexane to give (4-aminophenyl) (2-pyridyl)methanol (1 .90 g) as pale yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06172061B2
Source datasetuspto-grants-2001_01
ORD IDord-aeabc0c822a54a999a9229d25cba61ee
Source noteuspto-grants-2001_01