Methyl iodide → HCID 18472603, compound

Participants

Reaction Steps

In DMF (3ml) was dissolved N-[4-(piperidinomethyl)-phenyl]-7-phenylnaphthalene-2-carboxamide (300mg), and to the mixture was added methyl iodide (133 μl). The mixture was stirred at room temperature for 16 hours and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate to give 1-[4-(7-phenylnaphthalene-2-carboxamido)-benzyl]-1-methylpiperidinium iodide (Compound 59) (374mg) as pale yellow crystals.

Provenance & Evidence