HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 565916Generated: October 31, 2026
Tributylphosphine → HCID 10840676, compound
https://huagongshe.com/reaction/565916
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tributylphosphine | HCID 13831 | — |
| Reactant | (E)-N-[4-(chloromethyl)phenyl]3-(4-methylphenyl)cinnamamide | HCID 18472214 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 10840676 | HCID 10840676 | — |
Reaction Steps
In toluene (10ml) was dissolved (E)-N-[4-(chloro-methyl)-phenyl]-3-(4-methylphenyl)-cinnamamide (300mg), and to the mixture was added tributylphosphine (248 μl). The mixture was stirred at 80° C. for 3 days and cooled to room temperature. The resulting precipitate was filtered and recrystallized from ethyl acetate-methanol to give (E)-tributyl[4-[3-(4-methylphenyl)cinnamamido]benzyl]-phosphonium chloride (Compound 78) (389mg) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06172061B2 |
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| Source dataset | uspto-grants-2001_01 |
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| ORD ID | ord-55409068072b4df78049139564fd2786 |
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| Source note | uspto-grants-2001_01 |
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