Methyl iodide → HCID 86756159, compound

Participants

Reaction Steps

A solution of 1-(4-(3-phenylcinnamoylamino)-benzyl)piperidine (0.32g) and methyl iodide (0.15ml) in dimethylformamide (5ml) was stirred over night under nitrogen atmosphere at room temperature. The solvent was evaporated, and to the residue was added ethyl acetate. Precipitated crude crystal was filtered, which were recrystallized from ethanol to give 1-methyl-1-(4-(3-phenylcinnamoylamino)-benzyl)piperidinium iodide (Compound 85) (0.26g) as colorless crystals.

Provenance & Evidence