tert-butyl 6-(4-methylphenyl)-2H-1-benzopyran-3-carboxylate → 6-(4-methylphenyl)-2H-1-benzopyran-3-carboxylic acid

Participants

Reaction Steps

To tert-butyl 6-(4-methylphenyl)-2H-1-benzopyran-3-carboxylate (3.00 g) was added 4N hydrochloric acid-ethyl acetate (10 ml) at room temperature, and the mixture was stirred for 16 hours. To the reaction mixture was added hexane, and crystal was collected by filtration and washed with hexane to give 6-(4-methylphenyl)-2H-1-benzopyran-3-carboxylic acid (2.14 g) as pale yellow crystals.

Provenance & Evidence