HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-nitrophenyl)-1H-imidazole → 4-(1H-Imidazol-2-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-nitrophenyl)-1H-imidazole | HCID 11506596 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(1H-Imidazol-2-yl)aniline | HCID 23506927 | — |
Reaction Steps
A solution of 95 mg (0.5 mmol) of 2-(4-nitrophenyl)-1H-imidazole in 3 ml of ethanol was hydrogenated in the presence of 20 mg of palladium (10% on activated carbon) at RT and standard pressure. The reaction mixture was then filtered through Celite and the filtrate was concentrated under reduced pressure and dried. Yield: 91 mg (quant.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4dc29688a0734388b2180d2627f7334b |
| Source note | uspto-grants-2016_09 |