5-(4-Nitrophenyl)-2-(trifluoromethyl)-1H-imidazole → 4-[2-(Trifluoromethyl)-1H-imidazol-5-yl]aniline

Participants

Reaction Steps

A solution of 104 mg (0.4 mmol) of 5-(4-nitrophenyl)-2-(trifluoromethyl)-1H-imidazole in 10 ml of ethanol was hydrogenated in the presence of 15 mg of palladium (10% on activated carbon) at RT and standard pressure. The reaction mixture was then filtered through Celite and the filtrate was concentrated under reduced pressure and dried. Yield: 98 mg (quant.)

Provenance & Evidence