3-Butyn-1-OL → HCID 15475334, compound

Participants

Reaction Steps

In toluene (90 ml) were dissolved triphenylmethyl azide (8.23 g) and 3-butyn-1-ol (2.2 ml). The solution was heated for 60 hours under reflux. The reaction mixture was concentrated under reduced pressure. The concentrate was purified by means of a column chromatography (carrier: silica gel, 150 g, developing solvent: ethyl acetate). The resulting crystalline product was washed with isopropyl ether to give the title compound (3.06 g).

Provenance & Evidence